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Novo Nordisk’s Oral Wegovy Debuts With Strong Prescriptions as BMO Stays Cautious

BMO maintains a Market Perform rating despite early U.S. demand for the new pill.

Overview

  • Oral Wegovy, the first GLP-1 weight-loss pill, launched in the U.S. and recorded 18,410 prescriptions in its first full week.
  • Novo Nordisk shares were up about 26% for the year through Jan. 26, outpacing the broader market.
  • BMO raised its Novo Nordisk price target to $57 from $47 but kept a Market Perform rating.
  • The firm cut its 2025 Wegovy sales estimate to DKK 77.8 billion and projects roughly flat 2026 U.S. prescription volumes, implying negative year-over-year U.S. net sales.
  • BMO cited pricing pressure and recent flat TRx trends, noting a CVS exclusivity agreement as a tailwind, after Novo Nordisk lowered 2025 sales-growth guidance last year due to competition and compounding knock-offs.