Overview
- A randomized, nearly isocaloric trial assigned 31 women with overweight or obesity to two two-week eating windows: 8 a.m.–4 p.m. or 1 p.m.–9 p.m.
- With calories and nutrients held nearly constant, investigators found no short-term changes in insulin sensitivity, glucose, blood lipids, blood pressure, or inflammation markers.
- Later eating shifted internal circadian timing by roughly 40 minutes and was linked to later bedtimes and wake-times.
- Participants lost a small amount of weight despite the isocaloric design, suggesting unintended intake changes may occur.
- Published in Science Translational Medicine by the German Institute of Human Nutrition and collaborators, the work sets up future tests of time-restricted eating under calorie-restricted conditions and in longer, more diverse cohorts.